hormonal replacement therapy

systematic review meta-analysis network meta-analysis

Select cardiovascular prevention All type of patientprimary preventionsecondary prevention in patients with CAD       hormonal replacement therapy estrogen vs placebo or control      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	All cause death (28)cardiovascular events (26)Cardiovascular death (22)stroke (fatal and non fatal) (22)Non fatal MI (20)Venous thromboembolism (20)puylmonary embolism (12)Coronary event (9) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	All cause death	cardiovascular events
cardiovascular prevention
estrogen
WAVE, 2002      NCT	combined estrogen and progestogen	placebo			Low risk of bias	negative
EAGAR, 2006      NCT	combined estrogen and progestogen	placebo			Low risk of bias	negative
HERS, 1998          NCT	combined estrogen and progestogen	placebo			Low risk of bias	negative
EVTET, 2000	combined estrogen and progestogen	placebo			Low risk of bias	negative
Hall, 1998	combined estrogen and progestogen	placebo			Low risk of bias	negative
WHI, 2002	combined estrogen and progestogen	placebo			Low risk of bias	negative
WHISP, 2006	combined estrogen and progestogen	placebo			Low risk of bias	negative
WISDOM, 2007	combined estrogen and progestogen	placebo			Low risk of bias	negative
ERA (estrogen plus medroxyprogesterone), 2000      NCT	combined estrogen and progestogen	placebo			Low risk of bias	negative
WELL-HART (estrogen-progestin), 2003      NCT	combined estrogen and progestogen	placebo			Low risk of bias	negative
Schulman (NHLBI) (estrogen-progestogen), 2002      NCT	combined estrogen and progestogen	placebo			Low risk of bias	-
ERA (estrogen alone ), 2000        NCT	estrogen	placebo			Low risk of bias	negative
WELL-HART (estrogen alone), 2003      NCT	estrogen	placebo			Low risk of bias	negative
Schulman (NHLBI) (estrogen alone), 2002      NCT	estrogen	placebo			Low risk of bias	-
EPAT, 2001	estrogen	placebo			Low risk of bias	negative
ESPRIT, 2002	estrogen	placebo			Low risk of bias	negative
WEST, 2001	estrogen	placebo			Low risk of bias	negative