Drug eluting stent

Biolimus eluting stent - Everolimus eluting stent - Paclitaxel eluting stent - Sirolimus eluting stent - Zotarolimus eluting stent      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathmyocardial infarction (fatal and non fatal)

coronary artery disease  

abciximab  
Kim, 2010     abciximab-coated stentbare-metal stentExploratory -
biolimus eluting stent  
LEADERS, 2008      NCTbiolimus eluting stentsirolimus eluting stentnegative-9%25%
candesartan  
SYNTAX (unprotected left main sub group), 2009     DESCABGRisk of bias suggesting0%0%
dactinomycin eluting stent  
ACTION, 2004   dactinomycin eluting stentbare-metal stentsuggesting-56%161%
drug-eluting stents  
PASEO, 2009   drug-eluting stentsbare-metal stent -
DEDICATION, 2008      NCTdrug-eluting stentsbare-metal stentRisk of bias suggesting100%
GENIUS-STEMI, 2009     Genous stentbare-metal stentExploratory negative-∞%
Boudriot, 2008   DESCABGExploratory negative-61%
FREEDOM, 2012      NCTPCI with drug-eluting stentsCABGRisk of bias negative
Hong, 2005     PCI withdrug-eluting stentsCABGRisk of bias -
everolimus eluting stent  
FUTURE I, 2004     everolimus eluting stentbare-metal stentnegative∞%
FUTURE II, 2006   everolimus eluting stentbare-metal stentLow risk of bias -
SPIRIT I, 2005    NCTeverolimus eluting stentbare-metal stentExploratory negative∞%
BASKET-PROVE (EES), 2010   everolimus eluting stentbare-metal stentsuggesting-27%-36%
RESET, 2011    NCTeverolimus eluting stentsirolimus eluting stent -
PLATINUM, 2011      NCTeverolimus eluting stenteverolimus eluting stent -
SPIRIT II, 2006      NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias negative-65%
SPIRIT IV, 2010          NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting-17%-39%
SPIRIT III, 2008        NCTeverolimus eluting stentpaclitaxel eluting stentExploratory suggesting-2%-32%
COMPARE, 2009        NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting21%-48%
SPIRIT III (small vessel subgroup), 2009     everolimus eluting stentpaclitaxel eluting stentExploratory suggesting∞%∞%
SORT OUT IV, 2012      NCTeverolimus eluting stentsirolimus eluting stentRisk of bias -
ISAR-TEST 4 (EES vs SES)     everolimus eluting stentsirolimus eluting stentsuggesting
paclitaxel  
ISAR-DESIRE (PES vs PTCA), 2005     paclitaxel eluting stentballoon angioplastysuggesting-67%∞%
TAXUS I, 2003     paclitaxel eluting stentbare-metal stentLow risk of bias negative
TAXUS II, 2003      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-100%139%
TAXUS IV, 2004        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting11%146%
SCORE, 2004   paclitaxel eluting stentbare-metal stentsuggesting ∞%∞%
TAXUS V (all patients), 2005    NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-11%17%
TAXUS VI, 2005        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-100%4%
PASSION, 2006     paclitaxel eluting stentbare-metal stentRisk of bias negative-30%-16%
HAAMU-STENT, 2006   paclitaxel eluting stentbare-metal stentExploratory negative114%
Erglis, 2007     paclitaxel eluting stentbare-metal stentsuggesting-6%-33%
HORIZONS-AMI Stent, 2008     paclitaxel eluting stentbare-metal stentsuggesting1%-18%
TAXUS II (diabetics), 2003     paclitaxel eluting stentbare-metal stentLow risk of bias suggesting
TAXUS IV (diabetics), 2005      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting
TAXUS V (diabetics), 2005   paclitaxel eluting stentbare-metal stentLow risk of bias suggesting
TAXUS VI (diabetics), 2005      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting
SOS, 2008        NCTpaclitaxel eluting stentbare-metal stentExploratory suggesting138%-52%
TAXUS V small vessels sub groups   paclitaxel eluting stentbare-metal stent -
ASPECT, 2003      NCTpaclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias suggesting∞%
ELUTES, 2004     paclitaxel, non-polymeric eluting stentbare-metal stentnegative∞%
DELIVER, 2004   paclitaxel, non-polymeric eluting stentbare-metal stentRisk of bias negative-75%98%
PATENCY, 2002   paclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias negative-100%
TAXUS V ISR, 2006      NCTpaclitaxel eluting balloonbrachytherapyRisk of bias -
SYNTAX, 2009          NCTpaclitaxel eluting stentCABGRisk of bias suggesting 25%47%
ISAR-test (diabetics), 2006     paclitaxel eluting stentsirolimus eluting stentRisk of bias -
sirolimus eluting stent  
ISAR-DESIRE (SES vs PTCA), 2005     sirolimus eluting stentballoon angioplastysuggesting-33%∞%
Kochiadakis, 2007     sirolimus eluting stentbare-metal stentExploratory -
RAVEL, 2002      NCTsirolimus eluting stentbare-metal stentLow risk of bias suggesting-2%-21%
SIRIUS, 2003            NCTsirolimus eluting stentbare-metal stentLow risk of bias suggesting64%-13%
C-SIRIUS, 2004      NCTsirolimus eluting stentbare-metal stentLow risk of bias suggesting-50%
E-SIRIUS, 2003      NCTsirolimus eluting stentbare-metal stentsuggesting102%102%
SES-SMART, 2004     sirolimus eluting stentbare-metal stentsuggesting-100%-80%
DIABETES, 2005       sirolimus eluting stentbare-metal stentsuggesting
Pache et al, 2005     sirolimus eluting stentbare-metal stentsuggesting40%
PRISON II, 2006      NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting-33%
SCANDSTENT, 2006      NCTsirolimus eluting stentbare-metal stentsuggesting-3%
TYPHOON, 2006      NCTsirolimus eluting stentbare-metal stentsuggesting1%
SESAMI, 2007        NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting-57%-1%
DECODE, 2005      NCTsirolimus eluting stentbare-metal stentsuggesting-100%
SCORPIUS, 2007    NCTsirolimus eluting stentbare-metal stentsuggesting
MISSION, 2008   sirolimus eluting stentbare-metal stentRisk of bias suggesting-52%-38%
Ortolani et al, 2007     sirolimus eluting stentbare-metal stent -
Pasceri, 2003   sirolimus eluting stentbare-metal stent -
GISSOC II, 2010      NCTsirolimus eluting stentbare-metal stentExploratory suggesting
DEBATER (SES vs BMS), 2009   sirolimus eluting stentbare-metal stentsuggesting
BASKET-PROVE (SES), 2010   sirolimus eluting stentbare-metal stentRisk of bias suggesting-19%-65%
Ravel (diabetics), 2004     sirolimus eluting stentbare-metal stentsuggesting
SES-SMARt (diabetics), 2005     sirolimus eluting stentbare-metal stentsuggesting-100%-22%
DESSERT, 2008   sirolimus eluting stentbare-metal stentExploratory suggesting54%-19%
SIRIUS (diabetics), 2003     sirolimus eluting stentbare-metal stentLow risk of bias -
Díaz de la Llera, 2007     sirolimus eluting stentbare-metal stent -
RRISC, 2006    NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting∞%192%
SCANDSTENT (subgroup), 2006     sirolimus eluting stentbare-metal stentExploratory suggesting-100%
CRISTAL    NCTsirolimus eluting stentPTCA -
RIBS-II, 2008   sirolimus eluting stentPTCAsuggesting-3%-3%
SISR, 2007        NCTsirolimus eluting stentbrachytherapyRisk of bias suggesting∞%
PRECOMBAT, 2011    NCTsirolimus eluting stentCABG -
Thiele, 2009    NCTPCI withsirolimus ESMIDCABRisk of bias -
Tomai, 2008     sirolimus eluting stentpaclitaxel eluting stent -
TAXi, 2005     sirolimus eluting stentpaclitaxel eluting stentRisk of bias negative-35%
ISAR-DESIRE (SES vs PES), 2005     sirolimus eluting stentpaclitaxel eluting stentsuggesting100%-50%
ISAR-DIABETES, 2005     sirolimus eluting stentpaclitaxel eluting stentnegative-33%67%
SIRTAX (Windecker), 2005     sirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting-54%-21%
CORPAL, 2005   sirolimus eluting stentpaclitaxel eluting stentnegative-21%-18%
REALITY, 2006      NCTsirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting74%-14%
ISAR-SMART 3, 2006      NCTsirolimus eluting stentpaclitaxel eluting stentnegative-23%43%
Zhang (SES vs PES), 2006     sirolimus eluting stentpaclitaxel eluting stentExploratory negative-6%-36%
LONG DES II, 2006     sirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting∞%-22%
PROSIT, 2006   sirolimus eluting stentpaclitaxel eluting stentnegative-18%-2%
SORT OUT II, 2008      NCTsirolimus eluting stentpaclitaxel eluting stentnegative