PCI

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultreinfarctionAll cause death

acute myocardial infarction  

drug-eluting stents  
DEDICATION, 2008      NCTdrug-eluting stentsbare-metal stentRisk of bias suggesting100%
PASEO, 2009   drug-eluting stentsbare-metal stent -
paclitaxel  
HORIZONS-AMI Stent, 2008     paclitaxel eluting stentbare-metal stentsuggesting1%
PASSION, 2006     paclitaxel eluting stentbare-metal stentRisk of bias negative-30%
HAAMU-STENT, 2006   paclitaxel eluting stentbare-metal stentExploratory negative114%
PCI  
PRAGUE, 2000     systematic PCI (+stent)no systematic PCInegative-51%
WEST, 2006     systematic PCI (+stent)no systematic PCInegative-36%
CAPITAL AMI, 2005     systematic PCI (+stent)no systematic PCInegative-59%
GRACIA-1, 2004     systematic PCI (+stent)no systematic PCIRisk of bias negative-39%
SIAM III, 2002     systematic PCI (+stent)no systematic PCInegative-1%
C-PORT, 2002     primary PCIaccelerated t-PA -
STAT, 2001     primary stentingaccelerated t-PA -
STOPAMI 3, 2004     primary stentingballoon angioplasty -
ZWOLLE 6, 2005     primary stentingballoon angioplasty -
CADILLAC (no abciximab), 2002     primary stentingballoon angioplasty -
CADILLAC abciximab., 2002     primary stentingballoon angioplasty -
FRESCO, 1998     primary stentingballoon angioplasty -
Zwolle 5 (Suryapranata), 1998     primary stentingballoon angioplastysuggesting-79%-32%
Jaksch, 1998   primary stentingballoon angioplastysuggesting-63%-40%
GRAMI (Rodriguez), 1998     primary stentingballoon angioplastynegative-100%-50%
stent-PAMI (Grines), 1999     primary stentingballoon angioplastysuggesting-61%96%
PASTA (Saito), 1999     primary stentingballoon angioplastysuggesting-100%-58%
PRISAM (Kawashima), 1999   primary stentingballoon angioplastynegative-100%
STENTIM-2 (Maillard), 2000     primary stentingballoon angioplastynegative9%∞%
PSSAAMI (Scheller), 2001     primary stentingballoon angioplastysuggesting-100%100%
STOPAMI 2, 2002     primary stentingimmediate thrombolysis -
senior PAMI, 2005    NCTprimary PCIThrombolysisRisk of bias suggesting
primary angioplasty  
DANAMI-2, 1997         primary ballon angioplastyaccelerated t-PA -
Ribichini, 1996   primary ballon angioplastyaccelerated t-PA -
Garcia, 1997     primary ballon angioplastyaccelerated t-PA -
GUSTO 2B, 1997     primary ballon angioplastyaccelerated t-PA -
DeWood, 1989   primary ballon angioplastyduteplase -
Gibbons, 1993     primary ballon angioplastyduteplase -
O'Neill, 1986   primary ballon angioplastyintracoronary streptokinase -
Ribeiro, 1993   primary ballon angioplastystreptokinase -
Grinfeld, 1996   primary ballon angioplastystreptokinase -
Zijlstra, 1997     primary ballon angioplastystreptokinase -
Akhras, 1997   primary ballon angioplastystreptokinase -
Zwolle, 1994   primary ballon angioplastystreptokinasenegative -87%
Zijlstra , 1993     primary ballon angioplastystreptokinase -
PAMI, 1993     primary ballon angioplastyt-PA -
TRIANA, 2009    NCTprimary ballon angioplastytenecteplaseRisk of bias negative60%
PTCA  
PRAGUE-1, 2000     primary angioplastyimmediate thrombolysissuggesting
DANAMI-2, 2003   primary angioplastyimmediate thrombolysissuggesting-69%-24%
MAASTRICHT (Vermeer), 1999     primary angioplastyimmediate thrombolysisnegative
CAPTIM, 2002     primary angioplastyimmediate thrombolysisnegative
PRAGUE-2, 2003     primary angioplastyimmediate thrombolysissuggesting
AIR-PAMI, 2002     primary angioplastyimmediate thrombolysisnegative
ECSG, 1988   immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative-33%
TAMI 1 pilot, 1987   immediate systematic ballon angioplastyteno immediate angioplastyExploratory suggesting
Belenkie, 1991   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Topol, 1987   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Ellis, 1994   immediate systematic ballon angioplastyteno immediate angioplasty -
TAMI-5 (Califf), 1991   immediate systematic ballon angioplastyteno immediate angioplasty -
Erbel, 1989     immediate systematic ballon angioplastyteno immediate angioplasty -
MERLIN (Sutton), 2004     immediate systematic ballon angioplastyteno immediate angioplasty -
SWISS-SMASH, 1999   immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative-28%
TIMI 2A, 1988   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Belenkie, 1992   rescue PTCAno rescue PTCARisk of bias negative-81%
REACT (rescue PCI), 2005       rescue PTCAno rescue PTCAsuggesting -76%-51%
MERLIN, 2004       rescue PTCAno rescue PTCAnegative -31%-11%
RESCUE II, 2000     rescue PTCAno rescue PTCAnegative∞%
RESCUE, 1994   rescue PTCAno rescue PTCAnegative-47%
SWIFT, 1991   systematic ballon angioplastyno systematic angioplastyRisk of bias negative
SIAM, 1992   systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI II-A (defered)   systematic ballon angioplastyno systematic angioplasty -
Vermeer, 1999     systematic ballon angioplastyno systematic angioplasty -
TAMI 6, 1992   systematic ballon angioplastyno systematic angioplasty -
Barbash, 1990   systematic ballon angioplastyno systematic angioplasty -
TOPS, 1992   systematic ballon angioplastyno systematic angioplastyExploratory negative
Van den Brand, 1991   systematic ballon angioplastyno systematic angioplastyExploratory negative
Guerci, 1987   systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI 2, 1989   systematic ballon angioplastyno systematic angioplastyRisk of bias negative 11%
sirolimus eluting stent  
SESAMI, 2007        NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting-57%
TYPHOON, 2006      NCTsirolimus eluting stentbare-metal stentsuggesting1%
Díaz de la Llera, 2007     sirolimus eluting stentbare-metal stent -
MISSION, 2008   sirolimus eluting stentbare-metal stentRisk of bias suggesting-52%
DEBATER (SES vs BMS), 2009   sirolimus eluting stentbare-metal stentsuggesting
PROSIT, 2006   sirolimus eluting stentpaclitaxel eluting stentnegative-18%
Di Lorenzo et al., 2005     sirolimus eluting stentpaclitaxel eluting stentnegative-25%
Juwana, 2009     sirolimus eluting stentpaclitaxel eluting stentnegative44%
zotarolimus eluting stent  
ZEST AMI (vs PES), 2009      NCTzotarolimus eluting stentpaclitaxel eluting stentRisk of bias negative∞%
ZEST AMI (vs SES), 2009      NCTzotarolimus eluting stentsirolimus eluting stentnegative-24%