intensive blood pressure control

systematic review meta-analysis network meta-analysis

Select hypertension All type of patientDiabetic patientsNasopharyngeal carcinomaPatient with prior MI or with history of CHD       Treatment blood pressure target intensive blood pressure lowering strategies vs standard target       elderlynondiabetic kidney diseasetype 2 diabetes

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	All cause death (27)Cardiovascular death (21)cardiovascular events (20)stroke (fatal and non fatal) (17)End stage renal disease (15)Heart failure (15)myocardial infarction (fatal and non fatal) (15)non cardiovascular death (11)Serious adverse event (5)left ventricular hypertrophy (2) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	All cause death	Cardiovascular death
hypertension
intensive blood pressure lowering strategies
SPRINT, 2015      NCT	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie	test é		Risk of bias	suggesting
UKPDS-HDS, 1998	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		type 2 diabetes	Risk of bias	suggesting
JATOS, 2008	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		elderly	Risk of bias	negative
VANLISH, 2010	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		elderly	Risk of bias	negative
HOMED-BP, 2012	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie			Risk of bias	negative
SPS3, 2013      NCT	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie			Risk of bias	negative
Wei, 2013	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		elderly	Risk of bias	suggesting
PAST-BP, 2015	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie				negative
MDRD, 1994	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		nondiabetic kidney disease		suggesting
HOT, 1994	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie				negative
ABCD target (H) , 2000	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		type 2 diabetes		suggesting
AASK, 2002	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		nondiabetic kidney disease		negative
REIN-2, 2005	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		nondiabetic kidney disease		negative
ABCD target (N) , 2002	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		type 2 diabetes		suggesting
Toto, 1995	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		nondiabetic kidney disease		negative
ACCORD blood pressure, 2008        NCT	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie		type 2 diabetes	Risk of bias	suggesting
Cardio-Sis, 2009      NCT	more intensive blood pressure lowering strategie	less intensive blood pressure lowering strategie	test 1		Exploratory	suggesting