prevention of sudden death

systematic review meta-analysis network meta-analysis

Select ICD resynchronization (CRT) - defibrillators (ICD)antiarrythmic drugs primary preventionprimary prevention in post MI patientsuncoded clinical condition ***       cardiac resynchronization therapyCombined CRT + ICDImplantable cardioverter defibrillator therapy vs usual carevs ICD      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	All cause death (51)hospitalisation for heart failure (12)heart failure death (10)Sudden death (10) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	All cause death	hospitalisation for heart failure
ICD
not classified
MADIT, 1996	ICD	no ICD				-
resynchronization (CRT) - defibrillators (ICD)
not classified
RethinQ, 2007      NCT	Combined CRT + ICD	no CRT			Exploratory	negative
CARE-HF, 2005	CRT	no CRT				suggesting
COMPANION (CRT vs MT), 2004	CRT	no CRT			Risk of bias	negative
MIRACLE, 2002	CRT	no CRT				suggesting
MUSTIC-SR, 2001	CRT	no CRT				negative
MUSTIC AF, 2002	CRT	no CRT				negative
Garrigue, 2002	CRT	no CRT				-
PATH-CHF, 2002	CRT	no CRT				-
RD-CHF, 2003	CRT	no CRT				negative
AMIOVIRT, 2003	Combined CRT + ICD	no CRT no ICD				-
COMPANION (CRT+ICD vs MT), 2004	Combined CRT + ICD	no CRT no ICD				suggesting
CAT, 2002	ICD	no ICD				-
DEFINITE, 2004	ICD	no ICD				-
MADIT-II, 2002	ICD	no ICD				suggesting
SCD-HeFT (ICD vs placebo), 2005      NCT	ICD	no ICD				-
MADIT, 1996	ICD	no ICD				-
CABG-patch, 1997      NCT	ICD	no ICD				-
DINAMIT, 2004	ICD	no ICD				negative
MUSIT, 1999	ICD	no ICD				-
SCD-HeFT (ICD vs amiodarone), 2005      NCT	ICD	no ICD				-
AVID, 1997      NCT	ICD	no ICD				-
CASH, 2000	ICD	no ICD				-
CIDS, 2000	ICD	no ICD				-
Dutch trial, 1995	ICD	no ICD				negative
COMPANION (CRT+ICD vs CRT), 2004	Combined CRT + ICD	CRT				negative
CONTAK-CD , 2003	Combined CRT + ICD	ICD alone				-
MIRACLE-ICD-I, 2003	Combined CRT + ICD	ICD alone			Low risk of bias	negative
MIRACLE-ICD-II, 2004	Combined CRT + ICD	ICD alone			Low risk of bias	negative