gastric or gastro-oesophageal junction cancer (advanced)

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultdeath (overall survival) progression or death (progression free survival PFS)

immune checkpoint inhibition  

nivolumab  
ATTRACTION-2, 2017      NCTnivolumabplaceboLow risk of bias suggesting-37%
pembrolizumab  
KEYNOTE-059 single-arm      NCTpembrolizumabnil -
Keynote 061, 2018    NCTpembrolizumabpaclitaxel2L 2nd line PD-L1 positive Risk of bias negative -18%27%