Cisplatin - Gemcitabine - Ixabepilone      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultdeath (overall survival)

advanced breast cancer (metastatic)  

capecitabine  
Oshaughnessy, 2001     capecitabineCMF -
Stockler, 2011     capecitabinecyclophosphamide, methotrexate, and 5-fluorouracil -
GeparQuattro, 2010      NCTcapecitabine docetaxeldocetaxel -
Mavroudis, 2010     capecitabinedocetaxel + epirubicin -
Verma, 2005     capecitabine + docetaxeldocetaxel alone -
Miles, 2004     capecitabine + docetaxeldocetaxel alone -
O'Shaughnessy, 2002     capecitabine + docetaxeldocetaxel alone -
Hori     capecitabine MPAIV CT -
Talbot, 2002     capecitabinepaclitaxel -
Moiseenko, 2000     capecitabinepaclitaxel -
Jäger, 2010   capecitabinepegylated liposomal doxorubicin -
EORTC 10001 (Pajk), 2008     capecitabinevinorelbine -
cisplatin  
Costanza, 1999   carboplatin followed by CAFCAFsuggesting
Creagan ET, 1984   CAPCFPsuggesting
Cocconi, 1991   cisplatin + etoposideCMFsuggesting
Cocconi, 1999   CMF, cisplatin, etoposide, and doxorubicinCMFsuggesting
Cocconi G, 1996   MPEPIV or MPEMiCMFsuggesting
Kolaric, 1985   CAPCMFVPsuggesting
Eisen, 1998     EcisFECycloFnegative
Nielsen, 2000   EPI + CISEPIsuggesting
Kolaric, 1989   CAPFACsuggesting
Berruti A, 2002   cisplatin + epirubicinlonidamine + epirubicinnegative
Berruti B, 2002   cisplatin + epirubicinlonidamine + epirubicinsuggesting
Icli, 2002   VP-16+Ppaclitaxelsuggesting
Fountzilas, 2002       PCbPEnegative
gemcitabine  
Seidman, 2011     gemcitabine + docetaxel capecitabine + docetaxel -
Chan, 2009     gemcitabine + docetaxelcapecitabine plus docetaxel -
Nielsen, 2011     gemcitabine + docetaxeldocetaxel -
Feher, 2005     gemcitabineepirubicin -
Brufsky, 2011     gemcitabine + paclitaxel + bevacizumabpaclitaxel + bevacizumab -
Albain, 2008     gemcitabine + paclitaxelpaclitaxel monotherapy -
Martín, 2007     gemcitabine + vinorelbinevinorelbine monotherapy -
Papadimitriou, 2009       gemcitabine + weekly docetaxelweekly docetaxel -