cardiac arrest

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultSurvival to hospital discharge Return of spontaneous circulation

active compression-decompression CPR  

not classified  
Aufderheide, 2011   active compression-decompression CPRstandard CPRRisk of bias suggesting 26%

antiarrythmic drugs  

amiodarone  
ARREST, 1999     amiodaroneplaceboLow risk of bias suggesting
ALIVE, 2002     amiodaronelidocaineLow risk of bias suggesting

compression-only CPR  

not classified  
Rea, 2010    NCTcompression-only CPRstandard CPRnegative14%11%
Svensson, 2010     compression-only CPRstandard CPRnegative30%
Hallstrom, 2000     compression-only CPRstandard CPRRisk of bias negative40%
Hallstrom + preliminary study   compression-only CPRstandard CPR -

fibrinolysis  

t-pa  
Abu-Laban, 2002     t-PAplaceboLow risk of bias negative∞%-8%
tenecteplase  
TROICA, 2008      NCTtenecteplaseplaceboLow risk of bias negative-13%-13%
TICA, 2004     tenecteplaseplaceboLow risk of bias negative

modified resuscitation protocol  

not classified  
Jost, 2010     compressions firstdefibrillation firstnegative25%-3%
Baker, 2008     compressions firstdefibrillation firstnegative-40%-5%
Jacobs, 2005     compressions firstdefibrillation firstnegative-18%15%
Wik, 2003     compressions firstdefibrillation firstnegative52%22%
Aufderheide, 2011   active compression-decompression CPRstandard CPRRisk of bias suggesting 26%
Rea, 2010    NCTcompression-only CPRstandard CPRnegative14%11%
Svensson, 2010     compression-only CPRstandard CPRnegative30%
Hallstrom, 2000     compression-only CPRstandard CPRRisk of bias negative40%
Hallstrom + preliminary study   compression-only CPRstandard CPR -

omega-3 fatty acids  

fish oil  
Raitt , 2006    NCTfish oilplaceboLow risk of bias negative
SOFA , 2006      NCTfish oilplaceboLow risk of bias negative
Leaf, 2005     fish oilplacebosuggesting

Public Access Defibrillation  

not classified  
HAT      NCTAutomatic External DefibrillationCardiopulmonary Resuscitation -
PAD (Hallstrom), 2004           Automatic External DefibrillationCardiopulmonary Resuscitationnegative

vasopressin  

not classified  
Lindner, 1997     vasopressinepinephrineLow risk of bias suggesting
Li, 1999   vasopressinepinephrinesuggesting
Lee, 2000   vasopressinepinephrinenegative
Stiell, 2001       vasopressinepinephrineLow risk of bias negative
Wenzel, 2004     vasopressinepinephrinenegative