aortic stenosis

systematic review meta-analysis network meta-analysis

Select cholesterol lowering interventiontranscatheter aortic-valve implantation (TAVI) All type of patient       statinsstatins+ezetimibetranscatheter aortic-valve implantation (TAVI) atorvastatinrosuvastatinsimvastatinTAVI vs no TAVI      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	Cancer (1)All cause death (1)Death from any cause or major stroke (1)major stroke (1)stroke or TIA (1) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	Cancer	All cause death
cholesterol lowering intervention
atorvastatin
SALTIRE, 2005	atorvastatin	placebo	aortic stenosis		Low risk of bias	negative
rosuvastatin
ASTRONOMER, 2010	rosuvastatin	placebo	aortic stenosis		Low risk of bias	-
simvastatin
SEAS, 2008    NCT	ezetimibe+simvastatin	placebo	aortic stenosis		Low risk of bias	negative
transcatheter aortic-valve implantation (TAVI)
TAVI
PARTNER, 2010    NCT	transcatheter aortic valve implantation	standard therapy			Risk of bias	suggesting
PARTNER cohort A, 2011    NCT	transcatheter aortic valve implantation	surgical valve replacement				-