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PTCA
all percutaneous coronary intervention (PTCA, BMS, DES)
systematic review
meta-analysis
network meta-analysis
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acute myocardial infarction
coronary artery disease
stable angina
deferred angioplasty (>3 days) after thrombolysis
early angioplasty (<3 days) after thrombolysis
immediate PCI after thrombolysis
PCI
rescue PCI
transfer for primary angioplasty
vs medical treatment
vs no systematic PCI
vs Surgery
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Description
Synopsis
Comparison
Treatments
Patients
Characteristics
Method
Risk of bias
References
None
Tools
Indexation
Results
Global trial result
Main results
All results
All result tag
NCT results
All cause death (38)
CABG (38)
reinfarction (35)
stroke (fatal and non fatal) (35)
Major bleeding (29)
recurrent angina (27)
Long term death (21)
In-hospital death (21)
Emergency CABG (21)
Reocclusion (21)
Angina (17)
Cardiac death or MI (17)
myocardial infarction (fatal and non fatal) (15)
Deaths or MI (15)
Heart failure (15)
Angina (grade 2 or worse) in first year (9)
Non fatal MI (8)
PTCA (8)
Death, MI and stroke (8)
cardiac death (8)
Revascularization (8)
Minor bleeding (8)
Death, MI, ischameia (6)
death, reinfarctus, stroke (6)
Options
Numeric
bar chart
forest plot
medians
Trial
Studied trt
Control trt
patients
tags
ROB
Trial result
All cause death
CABG
acute myocardial infarction
PRAGUE-2, 2003
primary angioplasty
immediate thrombolysis
suggesting
DANAMI-2, 2003
primary angioplasty
immediate thrombolysis
suggesting
-24%
CAPTIM, 2002
primary angioplasty
immediate thrombolysis
negative
AIR-PAMI, 2002
primary angioplasty
immediate thrombolysis
negative
PRAGUE-1, 2000
primary angioplasty
immediate thrombolysis
suggesting
MAASTRICHT (Vermeer), 1999
primary angioplasty
immediate thrombolysis
negative
Ellis, 1994
immediate systematic ballon angioplastyte
no immediate angioplasty
-
SHOCK (Hochman), 1999
NCT
immediate systematic ballon angioplastyte
no immediate angioplasty
Risk of bias
suggesting
TAMI-5 (Califf), 1991
immediate systematic ballon angioplastyte
no immediate angioplasty
-
Topol, 1987
immediate systematic ballon angioplastyte
no immediate angioplasty
Exploratory
-
TAMI 1 pilot, 1987
immediate systematic ballon angioplastyte
no immediate angioplasty
Exploratory
suggesting
-1%
ECSG, 1988
immediate systematic ballon angioplastyte
no immediate angioplasty
Exploratory
negative
Belenkie, 1991
immediate systematic ballon angioplastyte
no immediate angioplasty
Exploratory
-
TIMI 2A, 1988
immediate systematic ballon angioplastyte
no immediate angioplasty
Exploratory
-
SWISS-SMASH, 1999
immediate systematic ballon angioplastyte
no immediate angioplasty
Exploratory
negative
∞%
MERLIN (Sutton), 2004
immediate systematic ballon angioplastyte
no immediate angioplasty
-
Erbel, 1989
immediate systematic ballon angioplastyte
no immediate angioplasty
-
TOAT, 2002
late PTCA
no PTCA
negative
113%
DECOPI, 2004
late PTCA
no PTCA
negative
-16%
Silva et al, 2005
late PTCA
no PTCA
negative
-100%
OAT, 2006
late PTCA
no PTCA
negative
4%
TOSCA-2, 2006
NCT
late PTCA
no PTCA
-
TOMIIS, 1994
late PTCA
no PTCA
negative
-24%
Horie et al, 1998
late PTCA
no PTCA
suggesting
-78%
REACT (rescue PCI), 2005
rescue PTCA
no rescue PTCA
suggesting
-51%
MERLIN, 2004
rescue PTCA
no rescue PTCA
negative
-11%
RESCUE II, 2000
rescue PTCA
no rescue PTCA
negative
∞%
RESCUE, 1994
rescue PTCA
no rescue PTCA
negative
-47%
Belenkie, 1992
rescue PTCA
no rescue PTCA
Risk of bias
negative
-81%
Van den Brand, 1991
systematic ballon angioplasty
no systematic angioplasty
Exploratory
negative
Vermeer, 1999
systematic ballon angioplasty
no systematic angioplasty
-
TOPS, 1992
systematic ballon angioplasty
no systematic angioplasty
Exploratory
negative
TIMI 2, 1989
systematic ballon angioplasty
no systematic angioplasty
Risk of bias
negative
14%
TIMI II-A (defered)
systematic ballon angioplasty
no systematic angioplasty
-
Barbash, 1990
systematic ballon angioplasty
no systematic angioplasty
-
TAMI 6, 1992
systematic ballon angioplasty
no systematic angioplasty
-
SWIFT, 1991
systematic ballon angioplasty
no systematic angioplasty
Risk of bias
negative
756%
SIAM, 1992
systematic ballon angioplasty
no systematic angioplasty
Exploratory
negative
Guerci, 1987
systematic ballon angioplasty
no systematic angioplasty
Exploratory
negative
coronary artery disease
INSPIRE, 2006
balloon angioplasty
medical treatment
Risk of bias
negative
94%
RITA 2, 1997
balloon angioplasty
medical treatment
Risk of bias
suggesting
2%
4%
SWISSI II, 2007
NCT
balloon angioplasty
medical treatment
Exploratory
suggesting
-70%
ACME, 1992
balloon angioplasty
medical treatment
Risk of bias
suggesting
9%
10%
ACIP, 1997
balloon angioplasty
medical treatment
Exploratory
negative
-81%
Sievers, 1993
balloon angioplasty
medical treatment
Risk of bias
negative
-100%
0%
ACME 2 (Folland), 1997
balloon angioplasty
medical treatment
Risk of bias
negative
-12%
194%
MASS, 1995
balloon angioplasty
medical treatment
Risk of bias
suggesting
0%
0%
BARI, 1996
NCT
balloon angioplasty
CABG
negative
18%
GABI, 1994
balloon angioplasty
CABG
negative
-57%
1456%
EAST, 1994
NCT
balloon angioplasty
CABG
negative
14%
∞%
Lausanne, 1994
balloon angioplasty
CABG
negative
288%
676%
MASS, 1995
balloon angioplasty
CABG
negative
-3%
∞%
CABRI, 1995
balloon angioplasty
CABG
negative
42%
1915%
ERACI, 1992
balloon angioplasty
CABG
negative
103%
∞%
RITA, 1993
balloon angioplasty
CABG
negative
-9%
1312%
Toulouse, 1992
balloon angioplasty
CABG
negative
-29%
600%
stable angina
ACME, 1992
balloon angioplasty
medical treatment
Risk of bias
suggesting
9%
10%
Sievers, 1993
balloon angioplasty
medical treatment
Risk of bias
negative
-100%
0%
ACIP, 1997
balloon angioplasty
medical treatment
Exploratory
negative
-81%
ACME 2 (Folland), 1997
balloon angioplasty
medical treatment
Risk of bias
negative
-12%
194%
INSPIRE, 2006
balloon angioplasty
medical treatment
Risk of bias
negative
94%
SWISSI II, 2007
NCT
balloon angioplasty
medical treatment
Exploratory
suggesting
-70%
MASS, 1995
balloon angioplasty
medical treatment
Risk of bias
suggesting
0%
0%
RITA 2, 1997
balloon angioplasty
medical treatment
Risk of bias
suggesting
2%
4%
BARI, 1996
NCT
balloon angioplasty
CABG
negative
18%
GABI, 1994
balloon angioplasty
CABG
negative
-57%
1456%
Lausanne, 1994
balloon angioplasty
CABG
negative
288%
676%
EAST, 1994
NCT
balloon angioplasty
CABG
negative
14%
∞%
CABRI, 1995
balloon angioplasty
CABG
negative
42%
1915%
MASS, 1995
balloon angioplasty
CABG
negative
-3%
∞%
Toulouse, 1992
balloon angioplasty
CABG
negative
-29%
600%
ERACI, 1992
balloon angioplasty
CABG
negative
103%
∞%
RITA, 1993
balloon angioplasty
CABG
negative
-9%
1312%
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