Everolimus eluting stent Drug eluting stent  

XIENCE 5 - Abbott XIENCE V - Guidant XIENCE V - XIENCE V      

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathmyocardial infarction (fatal and non fatal)

coronary artery disease  

FUTURE I, 2004     everolimus eluting stentbare-metal stentnegative∞%
FUTURE II, 2006   everolimus eluting stentbare-metal stentLow risk of bias -
SPIRIT I, 2005    NCTeverolimus eluting stentbare-metal stentExploratory negative∞%
BASKET-PROVE (EES), 2010   everolimus eluting stentbare-metal stentsuggesting-27%-36%
RESET, 2011    NCTeverolimus eluting stentsirolimus eluting stent -
PLATINUM, 2011      NCTeverolimus eluting stenteverolimus eluting stent -
SPIRIT II, 2006      NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias negative-65%
SPIRIT IV, 2010          NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting-17%-39%
SPIRIT III, 2008        NCTeverolimus eluting stentpaclitaxel eluting stentExploratory suggesting-2%-32%
COMPARE, 2009        NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting21%-48%
SPIRIT III (small vessel subgroup), 2009     everolimus eluting stentpaclitaxel eluting stentExploratory suggesting∞%∞%
SORT OUT IV, 2012      NCTeverolimus eluting stentsirolimus eluting stentRisk of bias -
ISAR-TEST 4 (EES vs SES)     everolimus eluting stentsirolimus eluting stentsuggesting
ESSENCE diabetes      NCTeverolimus eluting stentsirolimus ES -

stable angina  

FUTURE I, 2004     everolimus eluting stentbare-metal stentnegative∞%
FUTURE II, 2006   everolimus eluting stentbare-metal stentLow risk of bias -
SPIRIT I, 2005    NCTeverolimus eluting stentbare-metal stentExploratory negative∞%
SPIRIT II, 2006      NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias negative-65%
SPIRIT IV, 2010          NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting-17%-39%
SPIRIT III, 2008        NCTeverolimus eluting stentpaclitaxel eluting stentExploratory suggesting-2%-32%
COMPARE, 2009        NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting21%-48%
SORT OUT IV, 2012      NCTeverolimus eluting stentsirolimus eluting stentRisk of bias -
ISAR-TEST 4 (EES vs SES)     everolimus eluting stentsirolimus eluting stentsuggesting