Linagliptin insulin secretagogues  

BI-1356 - BI1356 - BI 1356 - Tradjenta - Linagliptin      

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Trial Studied trt Control trt patientstagsROB Trial resultcardiovascular eventsCardiovascular death

diabetes type 2  

Forst, 2010      NCTlinagliptinLow risk of bias -
CAROLINA, 2012      NCTlinagliptinglimepirideLow risk of bias suggesting-54%0%
Gallwitz, 2012      NCTlinagliptinglimepiride (add on MET)Low risk of bias -
Owens      NCTlinagliptinMetformin + sulfonylurea -
Del Prato      NCTlinagliptinplaceboLow risk of bias -
Taskinen      NCTlinagliptinplacebo (add on MET) -
Gomis, 2011      NCTlinagliptinplacebo (add on pioglitazone) -
Lewin, 2010    NCTlinagliptinplacebo (add on SU)Low risk of bias -