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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathCardiovascular death

diabetes type 2  

SHEP (diabetic subgroup), 1996   chlorthalidoneplaceboLow risk of bias suggesting -26%

hypertension  

VA-NHLBI, 1977   chlorthalidoneplacebonegative∞%∞%
SHEP, 1991      NCTchlorthalidoneplaceboLow risk of bias suggesting -12%-19%
SHEP-pilot, 1989   chlorthalidoneplaceboLow risk of bias negative
SHEP (diabetic subgroup), 1996   chlorthalidoneplaceboLow risk of bias suggesting -26%
SHEP-P (subgroup ), 1989   chlorthalidoneplaceboLow risk of bias suggesting∞%∞%
SHEP (subgroup ), 1991   chlorthalidoneplaceboLow risk of bias suggesting-7%-17%