Paclitaxel Taxanes  

Onxol - 7 epi Taxol - 7-epi-Taxol - Praxel - Paxene - Bris Taxol - Taxol A - Taxol - NSC125973 - NSC 125973 - NSC-125973 - Anzatax      

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Trial Studied trt Control trt patientstagsROB Trial resultMACE2 yr Death (all cause)

acute myocardial infarction  

PASSION, 2006     paclitaxel eluting stentbare-metal stentRisk of bias negative
HORIZONS-AMI Stent, 2008     paclitaxel eluting stentbare-metal stentsuggesting2%-17%
HAAMU-STENT, 2006   paclitaxel eluting stentbare-metal stentExploratory negative

advanced breast cancer (metastatic)  

Talbot, 2002   pacclitaxelcapecitabineExploratory negative
TOG, 2005   paclitaxelcisplatin, etoposideExploratory negative
ANZ TITG, 1999   paclitaxelCMFP 1st line Risk of bias suggesting
EORTC 10923, 2000   paclitaxeldoxorubicin 1st line Exploratory negative
ECOG E1193 (B), 2003   paclitaxeldoxorubicinExploratory negative
UKCCCR AB01, 1997   paclitaxel + epirubicinepirubicin, cyclophosphamide 1st line Exploratory suggesting
Fountzilas , 2008   Weekly PaclitaxelEvery three weeks Docetaxelnegative
Gradishar , 2009   Weekly PaclitaxelEvery three weeks DocetaxelExploratory negative
Khoo , 2006   split doseEvery three weeks Paclitaxel not previously treated by anthracycline negative
Frasci , 2006   Weekly PaclitaxelEvery three weeks Paclitaxelnegative
Sikov , 2002   Weekly PaclitaxelEvery three weeks Paclitaxelnegative
Frasci , 2005   Weekly PaclitaxelEvery three weeks Paclitaxelnegative
CLGB 9840 (Seidman), 2008   Weekly PaclitaxelEvery three weeks Paclitaxelsuggesting
Jassem, 2001   paclitaxel + doxorubicinfluorouracil, doxorubicin, cyclophosphamide 1st line Exploratory suggesting
CECOG BM1, 2005   gemcitabine, epirubicin, paclitaxelfluorouracil, epirubicin, cyclophosphamide 1st line Exploratory suggesting
Dieras, 1995   paclitaxelmitomycinExploratory negative

coronary artery disease  

ISAR-DESIRE (PES vs PTCA), 2005     paclitaxel eluting stentballoon angioplastysuggesting
TAXUS II, 2003      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-52%
SCORE, 2004   paclitaxel eluting stentbare-metal stentsuggesting 17%
TAXUS V (all patients), 2005    NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-30%
TAXUS VI, 2005        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-27%
HAAMU-STENT, 2006   paclitaxel eluting stentbare-metal stentExploratory negative
TAXUS II (diabetics), 2003     paclitaxel eluting stentbare-metal stentLow risk of bias suggesting
TAXUS IV (diabetics), 2005      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting
PASSION, 2006     paclitaxel eluting stentbare-metal stentRisk of bias negative
TAXUS VI (diabetics), 2005      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting
Erglis, 2007     paclitaxel eluting stentbare-metal stentsuggesting-56%
TAXUS V (diabetics), 2005   paclitaxel eluting stentbare-metal stentLow risk of bias suggesting
TAXUS V small vessels sub groups   paclitaxel eluting stentbare-metal stent -
HORIZONS-AMI Stent, 2008     paclitaxel eluting stentbare-metal stentsuggesting2%-17%
SOS, 2008        NCTpaclitaxel eluting stentbare-metal stentExploratory suggesting-25%
TAXUS IV, 2004        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-44%
TAXUS I, 2003     paclitaxel eluting stentbare-metal stentLow risk of bias negative-68%
PATENCY, 2002   paclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias negative-46%
ELUTES, 2004     paclitaxel, non-polymeric eluting stentbare-metal stentnegative-46%
ASPECT, 2003      NCTpaclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias suggesting65%
DELIVER, 2004   paclitaxel, non-polymeric eluting stentbare-metal stentRisk of bias negative-23%
TAXUS V ISR, 2006      NCTpaclitaxel eluting balloonbrachytherapyRisk of bias -
SYNTAX, 2009          NCTpaclitaxel eluting stentCABGRisk of bias suggesting 50%26%
ISAR-test (diabetics), 2006     paclitaxel eluting stentsirolimus eluting stentRisk of bias -

Head and neck cancer  

Hitt paclitaxel, 2005     paclitaxel based CTPFsuggesting

stable angina  

TAXUS VI, 2005        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-27%
TAXUS V (all patients), 2005    NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-30%
SCORE, 2004   paclitaxel eluting stentbare-metal stentsuggesting 17%
TAXUS IV, 2004        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-44%
TAXUS II, 2003      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-52%
TAXUS I, 2003     paclitaxel eluting stentbare-metal stentLow risk of bias negative-68%
PATENCY, 2002   paclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias negative-46%
DELIVER, 2004   paclitaxel, non-polymeric eluting stentbare-metal stentRisk of bias negative-23%
ELUTES, 2004     paclitaxel, non-polymeric eluting stentbare-metal stentnegative-46%
ASPECT, 2003      NCTpaclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias suggesting65%
SYNTAX, 2009          NCTpaclitaxel eluting stentCABGRisk of bias suggesting 50%26%