Pazopanib multi target TKI
systematic review meta-analysis network meta-analysis
 

Votrient - GW-780604 - GW780604 - GW 780604 - GW-786034B - GW786034B - GW 786034B      

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Trial Studied trt Control trt patientstagsROB Trial resultdeath (overall survival) progression or death (progression free survival PFS)

lung cancer (metastatic)  

Scagliotti, 2013     pazopanib pemetrexed -

renal-cell carcinoma (advanced)  

Sternberg, 2010     pazopanibplaceboLow risk of bias suggesting-54%
VEG105192, 2010        NCTpazopanibplacebosuggesting-9%-54%
COMPARZ, 2013      NCTpazopanibsunitinibnegative-9%5%

sarcoma  

PALETTE (van der Graaf), 2012      NCTpazopanib placebosuggesting



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