Ceritinib ALK inhibitors  

LDK378 - Zykadia - ceritinib      

Select             pdf
Trial Studied trt Control trt patientstagsROB Trial resultprogression or death (progression free survival PFS) death (overall survival)

advanced breast cancer (metastatic)  

Hyams      NCTcediranib + fulvestrantfulvestrant -

lung cancer (metastatic)  

Laurie, 2014     cediranib carboplatin and paclitaxel -
Goss, 2010     cediranib carboplatin and paclitaxel -
ASCEND-4, 2017      NCTceritinibchemotherapy1L 1st line nonsquamous NSCLC Risk of bias suggesting-45%-27%
Dy, 2013     cediranib gemcitabine and carboplatin -
ASCEND 5, 2017      NCTceritinibpemetrexed or docetaxel2L after crizotinib failure 2nd line crizotinib failure -