Docetaxel Taxanes  

RP-56976 - RP 56976 - NSC 628503 - Taxotere - Taxoltere metro - docetaxol      

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Trial Studied trt Control trt patientstagsROB Trial result

advanced breast cancer (metastatic)  

JCOG, 2005   docetaxeldoxorubicin + cyclophosphamide 1st line Exploratory negative
Blohmer, 2010   docetaxel + epirubicinepirubicin, cyclophosphamide 1st line Risk of bias negative
Rivera , 2008   Weekly DocetaxelEvery three weeks Docetaxel -
Tabernero , 2004   Weekly DocetaxelEvery three weeks Docetaxel -
Sedky , 2002   Weekly DocetaxelEvery three weeks Docetaxel -
Willemse , 2007   Weekly DocetaxelEvery three weeks Docetaxel -
Bontenbal, 2005   docetaxel + doxorubicinfluorouracil, doxorubicin, cyclophosphamide 1st line Risk of bias suggesting
Bonneterre, 2004   docetaxel + epirubicinfluorouracil, epirubicin, cyclophosphamideRisk of bias suggesting
TXT Group, 2002   docetaxelfluorouracil, vinorelbine 2nd line previous anthracycline Exploratory suggesting
304 Study Group, 1999   docetaxelmitomycin, vinblastine 2nd+ line previous anthracycline Risk of bias suggesting
Sjostrom, 1999   docetaxelsequential methotrexate and 5-fluorouracil 2nd+ line previous anthracycline Exploratory suggesting
HERNATA, 2011   docetaxel + trastuzumabvinorelbine, trastuzumab 1st line HER-2 positive Exploratory suggesting

lung cancer (metastatic)  

TAX 317 (Shepherd) 100mg/m2, 2000       docetaxel -
TAX 320 100mg/m2, 2000     docetaxel -
DISTAl 01 (Gridelli) , 2004     weekly docetaxel3-weekly docetaxel -
Camps     weekly docetaxel3-weekly docetaxel -
Schuette     weekly docetaxel3-weekly docetaxel -
Gervais     weekly docetaxel3-weekly docetaxel -
Lai     weekly docetaxel3-weekly docetaxel -
Chen     weekly docetaxel3-weekly docetaxel -
REVEL, 2014      NCTramucirumab + docetaxeldocetaxel aloneLow risk of bias -
Esteban, 2003     paclitaxel 80mg/m2m2docetaxel 36 mg/ -