Letrozole aromatase inhibitors
systematic review meta-analysis network meta-analysis
 

CGS-20267 - CGS 20267 - Fémara - Femara - letrozole      

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Trial Studied trt Control trt patientstagsROB Trial resultclinical benefit objective response (ORR)

advanced breast cancer (metastatic)  

Gershanovich, 1998   letrozoleaminoglutethimidenegative-19%-36%
Rose, 2003   letrozoleanastrozolenegative -15%-35%
Goss, 2007   letrozoleatamestane + toremifenenegative-4%-15%
Tominaga, 2003   letrozolefadrozolenegative -30%-58%
Buzdar, 2001   letrozolemegestrol acetatesuggesting-12%4%
Dombernowsky, 1998   letrozolemegestrol acetatenegative-8%-30%
Mourisden, 2001   letrozoletamoxifennegative -22%-33%



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