Lovastatin cholesterol lowering intervention  

Mevacor - MK803 - MK 803 - MK-803 - 6 Methylcompactin - 6-Methylcompactin - Monacolin K - Mevinolin - Lovastatin      

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathCoronary death

cardiovascular prevention  

CCAIT, 1994   lovastatinplacebosecondary preventionExploratory negative1%98%
MARS, 1993      NCTlovastatinplacebosecondary preventionExploratory negative∞%-100%
AFCAPS/TexCAPS, 1998     lovastatinplaceboprimary preventionLow risk of bias conclusive4%-27%
Excel, 1991   lovastatinplaceboExploratory negative178%136%
Weintraub, 1994     lovastatinplacebosecondary preventionLow risk of bias negative
AFCAPS/TexCAPS (diabetic sub group), 1998     lovastatinplacebodiabetic patients primary prevention Low risk of bias -
CRISP 20mg, 1994    NCTlovastatinplacebodiabeticExploratory -
ACAPS, 1994    NCTlovastatinplacebosecondary prevention cerebral vascular disease Exploratory suggesting-88%-100%
CRISP 40mg, 1994    NCTlovastatinplacebodiabeticExploratory -
AFCAPS (women subgroup) , 1998       LovastatinplacebowomenExploratory negative57%
Sahni, 1991   lovastatinusual caresecondary preventionRisk of bias negative-21%-51%
CLAPT, 1999     lovastatinusual caresecondary preventionExploratory negative-100%

diabetes type 2  

AFCAPS/TexCAPS (diabetic sub group), 1998     lovastatinplacebodiabetic patients primary prevention Low risk of bias -