insulin secretagogues - DPP-4 inhibitors

     

pathologytreatmentpatient Demonstrated benefit and harm k      
diabetes type 2alogliptinnot classified

versus

No demonstrated result for efficacy

9 trialsmeta-analysis
diabetes type 2alogliptinnot classified

versus placebo or control

No demonstrated result for efficacy

alogliptin inferior to placebo (add on MET) in terms of HbA1c goal <7% in Nauck, 2009

2 trialsmeta-analysis
diabetes type 2linagliptinnot classified

versus

No demonstrated result for efficacy

2 trialsmeta-analysis
diabetes type 2linagliptinnot classified

versus placebo or control

No demonstrated result for efficacy

4 trialsmeta-analysis
diabetes type 2linagliptinnot classified

versus SU

No demonstrated result for efficacy

2 trialsmeta-analysis
diabetes type 2saxagliptinnot classified

versus

No demonstrated result for efficacy

10 trialsmeta-analysis
diabetes type 2saxagliptinnot classified

versus biguanides

No demonstrated result for efficacy

1 trialmeta-analysis
diabetes type 2saxagliptinnot classified

versus placebo or control

No demonstrated result for efficacy

saxagliptin inferior to placebo (add on MET) in terms of HbA1c goal <7% in DeFronzo, 2009

saxagliptin inferior to placebo in terms of HbA1c goal <7% in SAVOR-TIMI 53, 2013

12 trialsmeta-analysis
diabetes type 2saxagliptinnot classified

versus SU

No demonstrated result for efficacy

2 trialsmeta-analysis
diabetes type 2sitagliptinnot classified

versus

No demonstrated result for efficacy

3 trialsmeta-analysis
diabetes type 2sitagliptinnot classified

versus alpha-glucosidase inhibitor

No demonstrated result for efficacy

1 trialmeta-analysis
diabetes type 2sitagliptinnot classified

versus placebo or control

No demonstrated result for efficacy

17 trialsmeta-analysis
diabetes type 2sitagliptinnot classified

versus biguanides

No demonstrated result for efficacy

4 trialsmeta-analysis
diabetes type 2sitagliptinnot classified

versus SU

No demonstrated result for efficacy

3 trialsmeta-analysis
diabetes type 2sitagliptinnot classified

versus TZD

No demonstrated result for efficacy

1 trialmeta-analysis
diabetes type 2vildagliptinnot classified

versus

No demonstrated result for efficacy

2 trialsmeta-analysis
diabetes type 2vildagliptinnot classified

versus alpha-glucosidase inhibitor

No demonstrated result for efficacy

3 trialsmeta-analysis
diabetes type 2vildagliptinnot classified

versus placebo or control

No demonstrated result for efficacy

24 trialsmeta-analysis
diabetes type 2vildagliptinnot classified

versus SU

No demonstrated result for efficacy

4 trialsmeta-analysis
diabetes type 2vildagliptinnot classified

versus biguanides

No demonstrated result for efficacy

4 trialsmeta-analysis
diabetes type 2vildagliptinnot classified

versus TZD

No demonstrated result for efficacy

6 trialsmeta-analysis