pre treatment for PCI

Description Results NMA

target vessel revascularization 0.56 [0.28; 1.11]

All cause death 1.59 [0.52; 4.86]

MACE 0.67 [0.40; 1.14]

stroke 0.85 [0.29; 2.53]

MI 0.40 [0.12; 1.27]

death, MI, stroke, or target vessel revascularization 1.04 [0.89; 1.22]

cangrelor up front (cangrelor administered before percutaneous coronary intervention and followed by clopidogrel) (n=4367)

vs.

clopidogrel up front (clopidogrel followed by placebo) (n=4355)

cangrelor then clopidogrel vs clopidogrel then placebo

double blind

Parallel groups

Sample size: 4367/4355

Primary endpoint: death, MI, ischemia-driven revascularization

FU duration: 48 h