pentasaccharide

     

pathologytreatmentpatient Demonstrated benefit and harm k      
thrombosis preventionfondaparinuxabdominal surgery

versus placebo or control

No demonstrated result for efficacy

fondaparinux inferior to placebo (on top intermittent pneumatic comp.) in terms of Major bleeding in APOLLO (Turpie), 2007 (abdominal surgery patients)

1 trialmeta-analysis
thrombosis preventionfondaparinuxabdominal surgery

versus Low molecular weight heparin

No demonstrated result for efficacy

1 trialmeta-analysis
thrombosis preventionfondaparinuxhip surgery

versus Low molecular weight heparin

No demonstrated result for efficacy

fondaparinux inferior to enoxaparin in terms of Symptomatic venous thromboembolism in PENTATHLON (Turpie), 2002 (hip surgery patients)

fondaparinux inferior to enoxaparin in terms of Symptomatic deep-vein thrombosis in PENTATHLON (Turpie), 2002 (hip surgery patients)

4 trialsmeta-analysis
thrombosis preventionfondaparinuxknee surgery

versus placebo or control

No demonstrated result for efficacy

1 trialmeta-analysis
thrombosis preventionfondaparinuxknee surgery

versus Low molecular weight heparin

No demonstrated result for efficacy

fondaparinux inferior to enoxaparin in terms of Major bleeding in PENTAMAKS (Bauer), 2001 (knee surgery patients)

2 trialsmeta-analysis
thrombosis preventionfondaparinuxmedical patients

versus placebo or control

No demonstrated result for efficacy

1 trialmeta-analysis
thrombosis preventionfondaparinuxorthopaedic surgery

versus Low molecular weight heparin

No demonstrated result for efficacy

1 trialmeta-analysis