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pathology

Demonstrated benefit and harm

k

diabetes type 2

versus

No demonstrated result for efficacy

Trial	control	p<0.05	harm	NS
Charpentier, 2001	glimepiride monotherapy vs metformin

Trial

Treatments

Patients

Method

Charpentier, 2001

glimepiride monotherapy (n=-9)

vs.

metformin monotherapy (n=-9)

Type 2 diabetic patients aged 35-70 years inadequately controlled by metformin monotherapy 2550 mg daily for at least 4 weeks

double-blind

Sample size: -9/-9

Primary endpoint:

FU duration: 20 weeks

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