familial hypercholesterolemia

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultCardiovascular deathNon fatal MI

cholesterol lowering intervention  

ezetimibe  
Enhance, 2008   ezetimibeplacebo (on top statins)Low risk of bias -
pactimibe  
CAPTIVATE, 2009      NCTpactimibeplaceboLow risk of bias -
torcetrapib  
RADIANCE 1, 2007      NCTtorcetrapibplaceboExploratory negative-100%∞%